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Abstract Inflammatory Bowel Disease (IBD), comprising Crohn’s Disease and Ulcerative Colitis, is a chronic inflammatory condition of the gastrointestinal tract with a remarkably high prevalence of psychiatric comorbidities, particularly Major Depressive Disorder (MDD)

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Although the methods reported in the literature are highly heterogeneous (i.e., different acquisition techniques, different voxel size and placement, and different post-processing), we provide a detailed description of the current methods for GSH measurement within the next sections, differentiating unedited and edited spectrum techniques