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increased if necessary up to 80 mg daily, dose increased in severe cases ▶ BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION Adult: 40 mg daily until oral administration can be resumed, injection to be given over at least 2 minutes NSAID-associated peptic ulcer disease ▶ ▶ BY MOUTH Adult: 40 mg once daily for 8 weeks Prophylaxis of NSAID-associated gastric ulcer in patients with an increased risk of gastroduodenal complications who require continued NSAID treatment | Prophylaxis of NSAID-associated duodenal ulcer in patients with an increased risk of gastroduodenal complications who require continued NSAID treatment ▶ ▶ BY MOUTH ▶ Adult: 20 mg daily Gastro-oesophageal reflux disease ▶ BY MOUTH ▶ Adult: 40 mg once daily for 4 or 8 weeks ▶ BY INTRAVENOUS INJECTION, OR BY INTRAVENOUS INFUSION Adult: 40 mg daily until oral administration can be resumed, injection to be given over at least 2 minutes Severe oesophagitis ▶ ▶ BY MOUTH Adult: 40 mg once daily for 8 weeks, continue as maintenance treatment if appropriate Severe oesophagitis, refractory to initial treatment ▶ ▶ BY MOUTH ▶ Adult: 40 mg twice daily Functional dyspepsia ▶ BY MOUTH Adult: 20 mg once daily for 4 weeks Uninvestigated dyspepsia ▶ ▶ BY MOUTH Adult: 40 mg once daily for 4 weeks Zollinger–Ellison syndrome (and other hypersecretory conditions) ▶ ▶ BY MOUTH ▶ Adult: Initially 80 mg daily (max

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