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Abbreviations AITD Autoimmune thyroid disease CAT Catalase FNA A fine needle aspiration G-6-Pase Glucose-6-phosphatase GD Graves’ disease GM Gut microbiota HT Hashimoto’s thyroiditis IgG Immunoglobulin G L-T4 Levothyroxine NIH National Institutes of Health PTU Propylthiouracil RAI Radioactive iodine therapy SOD Superoxide dismutase T3 Triiodothyronine T4 Thyroxine TCM Traditional Chinese medicine TGAb Thyroglobulin antibodies Th1/Th2 T-helper 1/T-helper 2 Th17/Treg T-helper 17/regulatory T cells TPOAb Thyroid peroxidase antibodies TSH Thyroid-stimulating hormone TSI Thyroid stimulating immunoglobulin Authors’ contributions Radwa H