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Abbreviations 5-FU: 5-fluorouracil ABCC2: ATP-binding cassette, subfamily C (CFTR/MRP), member 2 AKT1: v-akt murine thymoma viral oncogene homolog 1 ATP7B: ATPase, Cu 2+ transporting, β polypeptide BMP4: bone morphogenetic protein 4 BRCA1: breast cancer 1, early onset BRCA2: breast cancer 2, early onset CDDP: cis -diamminedichloroplatinum(II) CDK2: cyclin-dependent kinase 2 CTR1: copper transporter 1 DAPK3: death-associated protein kinase 3 DFS: disease-free survival DSB: double-strand break DYRK1B: dual-specificity Y-phosphorylation regulated kinase 1B EGFR: epidermal growth factor receptor EMT: epithelial-to-mesenchymal transition ER: endoplasmic reticulum ERCC1: excision repair cross-complementing rodent repair deficiency, complementation group 1 FA: Fanconi anemia FDA: Food and Drug Administration FGFR2: fibroblast growth factor receptor 2 GSH: reduced glutathione GST: glutathione S-transferase HCC: hepatocellular carcinoma HNSCC: head and neck squamous cell carcinoma HR: homologous recombination HSP: heat-shock protein HTS: high-throughput screening IL-7: interleukin-7 LCL: lymphoblastoid cell line LIPC: lipase, hepatic MAPK: mitogen-activated protein kinase MAP3K1: mitogen-activated protein kinase kinase kinase 1 METTL6: methyltransferase like 6 MLH1: mutL homolog 1 MMR: mismatch repair MOMP: mitochondrial outer membrane permeabilization MSH2: mutS homolog 2 mTOR: mammalian target of rapamycin NER: nucleotide excision repair NSCLC: non-small cell lung carcinoma OS: overall survival PARP1: poly(ADP-ribose) polymerase 1 PDXK: pyridoxal kinase PPARGC1B: peroxisome proliferator-activated receptor γ , coactivator 1 β PTPC: permeability transition pore complex RAF1: v-raf-1 murine leukemia viral oncogene homolog 1 ROS: reactive oxygen species SNP: single-nucleotide polymorphism TLS: translesion synthesis TSCC: tongue squamous cell carcinoma USP1: ubiquitin specific peptidase 1 VDAC1: voltage-dependent anion channel 1 References Peyrone M

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Short- and Long-Term Effects of a Prebiotic Intervention with Polyphenols Extracted from European Black Elderberry-Sustained Expansion of Akkermansia spp

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