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One isoform is predicted not to contain a targeting signal, but the other four are predicted to be variously targeted to the chloroplast, for secretion, or to the plasma membrane, possibly indicating that they all pass through the secretory system to the chloroplast
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Differential diagnoses include dopa‐responsive dystonia (DRD), Wilson's disease, Parkin‐associated parkinsonism, PTEN‐induced kinase 1 associated parkinsonism and neurodegeneration with brain ion accumulation
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