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41 PD‐1 clusters with T cell receptors (TCRs) upon binding to PD‐L1, forming negative co‐stimulatory micro‐clusters, inducing dephosphorylation of proximal TCR signalling molecules, suppressing T cell activation and blocking the TCR‐induced stop signal
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Number:10 kotak
Discovery of ZAP70 inhibitors by high-throughput docking into a conformation of its kinase domain generated by molecular dynamics
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