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They mitigate the oxidative damage to membrane phospholipids, such as phosphatidylcholine (PC) and sphingomyelin (SM), and restore ceramide (CER) synthesis, which promotes apoptotic pathways in melanoma cells without harming healthy melanocytes 162
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The upregulation of Wnt5a in HFSCs enhanced small RhoGTPase Cdc42 activity and caused alterations in the spatial expression of Cdc42 within HFSCs
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