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Glutathione dynamics determine the therapeutic efficacy of mesenchymal stem cells for graft-versus-host disease via CREB1-NRF2 pathway | Science Advances

Moreover, while topical application has demonstrated rapid and sustained anti-inflammatory effects, the pharmacokinetics, systemic effects, and long-term outcomes of oral administration are largely uncharacterized

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Further, acetylation of SOD1 at Lys70 impairs SOD1–CCS recognition and diminishes its enzymatic activity, changing the net charge of Lys70 within the electrostatic loop from approximately +1 to 0

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