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Furthermore, specific iron chelators (such as deferoxamine, deferiprone), chloroquine and its derivatives, antioxidants (e.g., vitamin E, alpha-lipoic acid, selenium), chloroquine analogs like Fer-1, and calreticulin have showcased therapeutic promise in preclinical trials for autoimmune ailments
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234 Besides standard pharmaceutical and translational challenges, stimuli-responsive therapeutics face additional, specific hurdles, which also depend on the stimulus being exploited (Table 2)
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