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In hepatocarcinoma, anti-apoptotic miRNAs like miR-21, miR-221/222, and miR-155 are overexpressed, leading to the downregulation of tumor suppressor genes like phosphatase and tensin homolog deleted on chromosome ten ( PTEN ), cyclin-dependent kinase inhibitor 1B ( DKN1B)/p27 , cyclin-dependent kinase inhibitor 1C ( CDKN1C )/ p57 , and toll-like receptor 3 (TLR3)
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One examines the predictors of visceral adipose tissue response to it in patients with HIV associated excess abdominal fat (a randomized controlled trial in PLoS One examining the predictors of treatment response to tesamorelin, a growth hormone releasing factor analogue that reduces visceral adipose tissue in patients with HIV associated excess abdominal fat)
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