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bGH transgenic mice have increased adipose tissue expression of the p85α regulatory sub-unit of the PI3K while the opposite was found in lit/lit mice (del Rincon et al., 2002
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In humans, the role of G6PD deficiency and hemolysis has been well documented, and the antioxidant nature of G6PD has underscored its protective effects against the development of a variety of other pathologies, including diabetes and CVD
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