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Altogether, the metabolomic data suggested that after phagocytosis microglia synthetized metabolites involved in oxidative stress resolution, in cell proliferation, and in cell recovery, by the generation of proteins and lipidic membranes that may have been degraded during the phagocytic process- Phagocytosis efficiency is preserved in post-phagocytic microglia The phagocytosis-induced oxidative stress and metabolic rewiring shown above suggested that microglial functionality may be compromised after phagocytosis
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