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Future research should focus on elucidating the specific mechanisms of oxidative stress rather than the general “antioxidant therapy,” including the specific molecules regulated by oxidative stress in particular diseases, the subspatial distribution of ROS and antioxidants, as well as the differences in oxidative stress states between animal models and humans

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There was also a significant increase in the levels of IL-6 in the plasma samples of T2DM subjects compared to healthy subjects ( Figure 3D )