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Stimulates glucose metabolism in conditions without oxygen and increases the amount of NAD + produced by mitochondria Enhances the function of cytochrome oxidase May mimic oxygen’s function in the mitochondria Functions as a powerful antioxidant Benefit with monoamine oxidase (MAO) inhibitor for antidepressant effects Neurotransmitter in the brain responsible for arousal, attention, memory and motivation MOTS-C Brief Overview Mitochondrial-derived peptide (MOTS-c) is a 16-amino acid peptide encoded by mitochondrial DNA

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The bacterial suspension was serially diluted after being resuspended in sterile PBS, and 100 μl bacterial solution was taken into 900 μl BHI broth containing 10 mM H 2 O 2 , 10 mM FeCl 3 , and 5 mM CuSO 4 for 1 h, respectively