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Full article: Inhibition effect of thymoquinone and lycopene compounds on glutathione reductase enzyme activity purified from human erythrocytes
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This mechanism is consistent with the known thiol oxidase activity of ebselen 38 and would function through the formation of a transient selenylsulphide bond which is then rearranged by selenyl-thiol exchange to yield the SOD1 disulphide and free ebselen selenol (2-hydroseleno- N -phenylbenzamide)
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