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As far as formulation strategy, the BA of BCS Class II drugs can be enhanced either by improving their dissolution rate (Class IIa) or by enhancing solubility (Class IIb) via various formulation techniques such as particle size reduction, salt formation, surfactants, and amorphous solid dispersions

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Effects tend to wear off around 6 hours, too, so you and your provider can decide to have you take 2 to 3 doses for all-day symptom relief