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Catalytic cycle of P. falciparum glutathione reductase. | Download Scientific Diagram
Case presentation A 39-year-old male, an ex-smoker with no significant past medical history aside from a stab wound in 2014 treated with exploratory laparoscopy and repair of gastric wall lacerations, presented with dizziness, nausea, vomiting, diarrhea, palpitations, and syncope over the past few days
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Song et al showed that decreasing periplasmic GSH by deleting the GSH exporter CydD triggers the CpxR/SoxS two-component systems, upregulating the AcrAB-TolC pump and lowering intracellular drug accumulation
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