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Synaptic and extrasynaptic NMDAR activation exert opposing neural protective and neurotoxic effects, respectively, and these processes involve a variety of corresponding neuroprotective and apoptotic pathways ( Metabotropic Glutamate Receptors Glutamate can also activate a type of G-protein-coupled receptors known as metabotropic glutamate receptors (mGluRs)
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doi: 10.3390/antiox8020048 [DOI] [PMC free article] [PubMed] [Google Scholar] Benchoam D, Semelak JA, Cuevasanta E, et al
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