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For example, GSH-supported formation of Cu + or Fe 2+ can promote Fenton-like reactions that convert H 2 O 2 into highly reactive radicals, thereby damaging cellular macromolecules and promoting multiple forms of cell death 181,182
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Immunopurification and mass spectrometry revealed phosphorylated sites in the α 1D -AR that were not conserved among the other α 1 -ARs, strongly indicating that site-specific phosphorylation may be a contributing factor to the differential signaling and regulation of these receptors
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