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Mechanisms of Disease: metabolic effects of growth hormone and insulin-like growth factor 1 | Nature Reviews Endocrinology
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Designed in the 1990s by Frank Ng's team at the Howard Florey Institute in Melbourne (Australia) , clinically developed by Metabolic Pharmaceuticals through phase IIb in the obesity indication, AOD-9604 represents one of the first successful examples of pharmacological uncoupling between GH's lipolytic effect and its undesirable anabolic / hyperglycemic effects
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