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4 The peptide’s N-terminal residues insert deep into the transmembrane core of the receptor, where they trigger the conformational change that activates G-protein signaling, while the helical body of the peptide is held by the receptor’s extracellular domain

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Statistical analyses Data were analyzed using unpaired t-test with Welch’s correction or one-way or two-way ANOVA with Bonferroni or Dunnett’s post-hoc test