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Further investigation showed that CPs first reduce the level of skin oxidation, inhibit the expression of the key transcription factor AP-1 (c-Jun and c-Fos), then activate the TGF-β/Smad signaling pathway to promote collagen synthesis, inhibit the expression of MMP-1/3 to inhibit collagen degradation, and inhibit skin inflammation to alleviate skin aging in mice
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[DOI] [PMC free article] [PubMed] [Google Scholar] 193.Yamada H., Miura H., Suzuki Y., Koike S., Shimamoto S., Kobayashi Y
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