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The liberation of fatty acids by Atg1 during fasting contributes to enhanced mitochondrial oxidative capacity (Lettieri-Barbato et al., 2018)

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Pancreatic β-cell-specific knockout of X-box-binding protein-1 (XBP-1), a key transcription factor in ER stress, resulted in hyperglycemia and diet-induced insulin resistance resulting from β-cell dysfunction in mice [139,144]