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[DOI] [PMC free article] [PubMed] [Google Scholar] 468.Kalkavan H., Chen M.J., Crawford J.C., Quarato G., Fitzgerald P., Tait S.W.G., Goding C.R., Green D.R
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Once an ADC enters a tumor cell, the disulfide bond is reduced to thiol groups under the high GSH concentration, breaking the linker and releasing the drug
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