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But when exposed to oxidative stress, KEAP1/CUL3 polyubiquitination is hindered, thereby leading NRF2 to be released and then translocated to the nucleus, where NRF2 binds to the Antioxidant Response Element (ARE) and triggers the activation of a variety of antioxidant genes (Ganesh Yerra et al., 2013)
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Packaging:60 in Bottle
doi: 10.1152/ajpgi.1990.259.4.G618
Supports cognitive function and brain health
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