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Additionally, the GLYR1-catalyzed glyoxylate to glycolate conversion in the cytosol and the GOX-catalyzed glycolate to glyoxylate conversion in peroxisome may form a futile cycle that consumes NADPH in hpr1 , whereas the deficiency of GLYR1 in this background saves energy
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Acknowledgements This open-access review paper was supported by The project New Technologies for Translational Research in Pharmaceutical Sciences /NETPHARM, project ID CZ.02.01.01/00/22_008/0004607, is co-funded by the European Union, and the Erasmus+ Programme of the European Union, Key Action 2: Strategic Partnerships, Project no
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