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To identify potential off-target substrates, we searched enriched motifs against the human proteome, using the enrichment score of the IL-1Ξ² motif (cleavage between Glu 18 and Asp 19) as the cutoff for predicted cleavage activity (Fig
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40 A fresh solution was prepared for the oxidation by mixing 4.5 mL of a 90% formic acid in water with 0.5 mL of hydrogen peroxide and 0.5 g of solid phenol
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