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In the case of mass spectrometry (MS)- based metabolomics, several strategies are use, e.g., desorption electrospray ionization mass spectrometry (DESI-MS) or flow injection analysis-MS (FIA-MS), or in combination with separation techniques such as gas chromatography-mass spectrometry (GC-MS), liquid chromatography-mass spectrometry (LC-MS), or capillary electrophoresis-MS (CE-MS), to increase separation and better identification and quantitation of the metabolites present in a cell extract ( In order to maximize the effectiveness of in vitro metabolomic studies for hepatotoxicity, it is important to have a comprehensive coverage of the cell’s metabolome

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This means training sessions may feel more sustainable over time, particularly during endurance-focused training blocks or calorie-restricted phases