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The formulation surrounding GHK-Cu can affect: Peptide stability Solubility Release from the vehicle Interaction with the stratum corneum Retention within skin Availability of the peptide after application That is why topical-delivery research increasingly investigates carrier systems rather than evaluating the active ingredient alone
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Subsequent research has identified vascular injury and endothelial dysfunction as key contributors to the development of radiation-induced cardiomyopathy (91,92), primarily due to the heightened sensitivity of endothelial cells to radiation (92)
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