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UPR has three important sensors, namely protein kinase R-like ER kinase (PERK), inositol requiring enzyme 1 (IRE1), and activating transcription factor 6 (ATF6), which activate ERS markers C/EBP homologous protein (CHOP) and caspase-12 after separation [110, 111]
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Zinc’s antioxidant capabilities and involvement in hormonal balance may have implications for lowering oxidative stress, even though there is little direct study on its effects on adrenal hormone imbalance-related oxidative damage (150)
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