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Luteolin sensitizes the antiproliferative effect of interferon α/β by activation of Janus kinase/signal transducer and activator of transcription pathway signaling through protein kinase A-mediated inhibition of protein tyrosine phosphatase SHP-2 in cancer
251,252 Moreover, CTLA-4 blockade enhances CD28 costimulation and promotes glycolysis in T cells
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