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By inhibiting NNMT and preserving NADβΊ, 5-Amino-1MQ indirectly boosts SIRT1 activity , leading to: β Increased fat oxidation β SIRT1 activates PGC-1Ξ± (peroxisome proliferator-activated receptor gamma coactivator 1-alpha), a master regulator of mitochondrial biogenesis and fat metabolism
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