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The Effects of Proton Pump Inhibitors in Acid Hypersecretion-Induced Vitamin B12 Deficiency: A Systematic Review (2022) | Cureus
Oral administration subjects the peptide to gastric degradation, which is why most peptides cannot be taken orally
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The rest of the copper (≈1000 µg per liter plasma) is bound to ceruloplasmin (65%, approximately), transcuprein (12%), and other components of low molecular weight
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